Quantitative assessment of muscle fatigue during rowing ergometer exercise using wavelet analysis of surface electromyography (sEMG).

In this paper, we present a quantitative assessment of muscle fatigue using surface electromyography (sEMG), a widely recognized method that is conducted through various analytical approaches, including analysis of spectral and time-frequency distributions. Existing research in this field has demonstrated considerable variability in the computational methods used. Although some studies highlight the efficacy of wavelet analysis in dynamic motion, few offer a comprehensive method for determining fatigue and applying it to specific movements. Previous research has focused primarily on discerning differences based on sport type or gender, with a notable absence of studies that presented results for quantifying fatigue during exercise with rowing ergometers. Developing on our previous work, where we introduced a method for determining muscle fatigue through wavelet analysis, considering biomechanical aspects of limb position changes, this current article serves as a continuation. Our study refines the research approach for a selected group, focusing on fatigue determination using the previously established method. The results obtained confirm the effectiveness of DWT analysis in assessing muscle fatigue, as evidenced by the achievement of negative values of the regression coefficients of Median Frequency (MDF) during exercises performed to maximal fatigue. Furthermore, it has been confirmed that the homogeneity of the group and, in the case of the examined group, the results previously achieved or lower limb strength do not have an impact on the results. Finally, we discuss the main limitations of our study and outline the subsequent steps of our investigation, providing valuable information for future investigations in this field.

Basilar tip fenestration giving rise to Percheron's and mesencephalic arteries.

The basilar bifurcation region is a common site for intracranial aneurysms, as well as it gives rise to a group of perforating arteries that supply the mesencephalon and the thalamus. Complex vascular microanatomy poses a diagnostic and therapeutic challenge for neurosurgeons, neuroradiologists and neurologists. In this paper, we present a previously unreported case of basilar tip fenestration that gave rise to five perforating arteries: the artery of Percheron and four mesencephalic arteries. Due to invaluable clinical significance, the possibility of such a variant must be considered during performing various neurovascular procedures, since e.g., embolization of the fenestration misdiagnosed as an aneurysm would inevitably lead to severe neurological complications (consciousness disturbances, quadriplegia, and sensory loss). Comprehensive knowledge of the neuroanatomy and neuroembryology is crucial to safe execution of intracranial interventions.

Relationship between EMG and fNIRS during Dynamic Movements.

In the scientific literature focused on surface electromyography (sEMG) and functional near-infrared spectroscopy (fNIRS), which have been described together and separately many times, presenting different possible applications, researchers have explored a diverse range of topics related to these advanced physiological measurement techniques. However, the analysis of the two signals and their interrelationships continues to be a focus of study in both static and dynamic movements. The main purpose of this study was to determine the relationship between signals during dynamic movements. To carry out the analysis described, the authors of this research paper chose two sports exercise protocols: the Astrand-Rhyming Step Test and the Astrand Treadmill Test. In this study, oxygen consumption and muscle activity were recorded from the gastrocnemius muscle of the left leg of five female participants. This study found positive correlations between EMG and fNIRS signals in all participants: 0.343-0.788 (median-Pearson) and 0.192-0.832 (median-Spearman). On the treadmill, the signal correlations between the participants with the most active and least active lifestyle achieved the following medians: 0.788 (Pearson)/0.832 (Spearman) and 0.470 (Pearson)/0.406 (Spearman), respectively. The shapes of the changes in the EMG and fNIRS signals during exercise suggest a mutual relationship during dynamic movements. Furthermore, during the treadmill test, a higher correlation was observed between the EMG and NIRS signals in participants with a more active lifestyle. Due to the sample size, the results should be interpreted with caution.

Wavelet analysis of the EMG signal to assess muscle fatigue in the lower extremities during symmetric movement on a rowing ergometer.

PURPOSE: The aim of this publication was to propose a method to determine changes in fatigue in selected muscle groups of the lower extremity during dynamic and cyclical motion performed on a rowing ergometer. The study aimed to use the discrete wavelet transform (DWT) to analyze electromyographic signals (EMG) recorded during diagnostic assessment of muscle and peripheral nerve electrical activity (electroneurography) using an electromyography device (EMG). METHODS: The analysis involved implementing calculations such as mean frequency (MNF) and median frequency (MDF) using the reconstructed EMG signal through DWT. The study examined the efficacy of DWT analysis in assessing muscle fatigue after physical exertion. RESULTS: The study obtained a negative regression coefficient for DWT analysis in all muscles except for the right gastrocnemius (GAS). The results suggest that DWT analysis can be an effective tool for evaluating muscle fatigue after physical exertion. CONCLUSIONS: The use of DWT in the analysis of EMG signals during rowing ergometer exercises has shown promising results in assessing muscle fatigue. However, additional investigations are necessary to confirm and expand these findings. This publication addresses the literature gap on the determination of muscle fatigue considering motion analysis on a rowing ergometer using the discrete wavelet transform. Previous studies have extensively compared and analyzed methods such as the Fourier transform (FFT), short-time Fourier transform (STFT), and wavelet transform (WT) for muscle fatigue analysis. However, no previous work has specifically examined the assessment of muscle fatigue by incorporating DWT analysis with motion analysis on a rowing ergometer.

Mechanism of Spontaneous Intracerebral Hemorrhage Formation: An Anatomical Specimens-Based Study.

BACKGROUND: Despite advances in understanding various risk and prognostic factors, spontaneous intracerebral hemorrhage is connected to very high morbidity and mortality, while the therapy is mainly supportive. Understanding of the pathophysiology of initial hematoma expansion is limited due to insufficient clinical data and lack of a suitable animal model. METHODS: We injected 40 anatomic specimens of the basal ganglia with contrast medium, scanned them with a micro-computed tomography scanner and analyzed the results of radiological studies, direct and histological examinations. RESULTS: In 9 cases, micro-computed tomography and histological examinations revealed contrast medium extravasations mimicking intracerebral hematomas. The artificial hematomas spread both proximally and distally along the ruptured perforator and its branches in the perivascular spaces and detached the branches from the adjacent neural tissue leading to destruction of the tissue and secondary extravasations. Moreover, some contrast extravasations skipped to the perivascular spaces of unruptured perforators, created further extravasation sites and aggravated the expansion of the artificial hematoma. There was no subarachnoid extension of any artificial hematoma. CONCLUSIONS: We postulate that a forming basal ganglia intracerebral hematoma spreads initially in the perivascular space, detaches the branches from the neural tissue and causes secondary bleeding. It can also skip to the perivascular space of a nearby perforator. The proposed mechanism of hematoma initiation and formation explains extent of damage to the neural tissue, variability of growth in time and space, creation of secondary bleeding sites, and limited usefulness of surgical interventions. The model is reproducible, the extent of the artificial hematoma can be easily controlled, the rupture sites of the perforating arteries can be determined, and preparation of the model does not require specialized, expensive equipment apart from the micro-computed tomography scanner.

Correlation of Bone Material Model Using Voxel Mesh and Parametric Optimization.

The authors present an algorithm for determining the stiffness of the bone tissue for individual ranges of bone density. The paper begins with the preparation and appropriate mechanical processing of samples from the bovine femur and their imaging using computed tomography and then processing DICOM files in the MIMICS system. During the processing of DICOM files, particular emphasis was placed on defining basic planes along the sides of the samples, which improved the representation of sample geometry in the models. The MIMICS system transformed DICOM images into voxel models from which the whole bone FE model was built in the next step. A single voxel represents the averaged density of the real sample in a very small finite volume. In the numerical model, it is represented by the HEX8 element, which is a cube. All voxels were divided into groups that were assigned average equivalent densities. Then, the previously prepared samples were loaded to failure in a three-point bending test. The force waveforms as a function of the deflection of samples were obtained, based on which the global stiffness of the entire sample was determined. To determine the stiffness of each averaged voxel density value, the authors used advanced optimization analyses, during which numerical analyses were carried out simultaneously, independently mapping six experimental tests. Ultimately, the use of genetic algorithms made it possible to select a set of stiffness parameters for which the error of mapping the global stiffness for all samples was the smallest. The discrepancies obtained were less than 5%, which the authors considered satisfactory by the authors for such a heterogeneous medium and for samples collected from different parts of the bone. Finally, the determined data were validated for the sample that was not involved in the correlation of material parameters. The stiffness was 7% lower than in the experimental test.

Identification of muscle movements and activity by experimental methods for selected cases - stage #2.

PURPOSE: The aim of the performed tests and static measurements was to determine the torque and to determine the activity curve for individual muscle heads during the flexion-extension movement in the elbow joint. METHODS: Both heads of the biceps branchial muscle and the triceps muscle of the arm - long head and lateral head - were examined. Static measurements were carried out for four selected positions of the upper limb. For each pose, a measurement series consisting of five attempts of ten seconds of effort was performed. Isometric contraction was performed as 100% of the maximum voluntary MVC contraction. Dynamic measurements were carried out when working in isokinetic conditions. In both stages, an EMG and a Biodex isokinetic dynamometer were used. RESULTS: During the analyses, it was assumed that the average value of the torque is equal to the approximate value of the torque of a given head under static conditions. The value of the torque of the biceps brachial muscle, long head was 48.04 Nm and for the short head - 45.82 Nm. For the triceps muscle of the long head, this value was 52.52 Nm and for the lateral head - 38.06 Nm. On the basis of dynamic measurements, four activation curves were determined for each of the heads during the 7-second task. For the curves, the sum value of muscle activity in a given period of time was calculated as the area under the curve. CONCLUSIONS: Both parts of the series of articles present a series of experimental studies conducted in order to determine the parameters for one patient, for whom a personalized numerical model of the upper limb was ultimately created. Static measurements were carried out to determine the maximum values of the moments of forces. Dynamic measurements allowed for the determination of activity curves during the movement of the upper limb.

Identification of muscle movements and activity by experimental methods for selected cases - stage#1.

PURPOSE: The aim of this study was to determine the position where the most activated and isolated individual muscles were. In the next steps, the selected limb positions will be used to determine the maximum values of isometric forces of the individual muscle heads based on the Hill model. METHODS: In order to determine the sought muscle activation, an electromyograph was used. Isometric contraction measurements were carried out for seven series of tests. Isometric contraction was performed as 100% MVC. RESULTS: For the long head of the biceps muscle, in the case of bending in the shoulder joint, angle of 75° was selected and for abduction in the shoulder joint - 90°. Internal rotation in the shoulder joint was omitted because of lower activation values. For the short head of the biceps muscle, the angle characterized by the greatest activity of the head was the angle of 115° in flexion at the elbow joint. The selected angle was 30° for shoulder extension and 110° for shoulder adduction. For the lateral head of the triceps brachial muscle, measurements showed that the angle at which the lateral head was most activated is 115°. CONCLUSIONS: The aim of this study was to determine the positions of the arm muscles that activate and isolate individual heads the most. The research presented and achieved results concern one specific person for whom a personalized numerical model was developed to represent the flexion-extension movement at the elbow joint. The performed tests can also be a preliminary assessment of the upper limb positions, for which wider conclusions could be drawn in the case of measurements on a larger number of participants.

Research of Vibrations of an Armoured Personnel Carrier Hull with FE Implementation.

Modern wheeled armoured vehicles can perform a variety of tasks, making the development of weapon systems that can be safely and effectively integrated with the vehicle structure an area of interest. Due to the cost of implementing new models, it is more economical to test potential configurations using numerical methods, such as the finite element method. The numerical model has been validated to confirm the reliability of the obtained results. Modal tests were also performed using four configurations to identify the frequency and mode shape of natural vibrations occurring within the support structure. In an experimental setting, hull vibrations were forced using the modal hammer testing method. The modal assurance criterion (MAC) and the authors' procedure were used to confirm the experimental and numerical test results. Additional testing in the form of impact loads was carried out for turret-containing structures. Structural strain at indicated points and forces transmitted by brackets to the bottom of the hull were compared.

Assessment of the Impact of Decellularization Methods on Mechanical Properties of Biocomposites Used as Skin Substitute.

This work aimed to assess the impact of acellularization and sterilization methods on the mechanical properties of biocomposites used as a skin substitute. On the basis of the statistical analysis, it was ascertained that the values of the Young modulus for the samples before the sterilization process-only in the cases of substances such as: trypsin, 15% glycerol and dispase-changed in a statistically significant way. In the case of dispase, the Young modulus value before the sterilization process amounted to 66.6 MPa, for trypsin this value equalled 33.9 MPa, whereas for 15% glycerol it was 11 MPa. In the case of samples after the completion of the sterilization process, the analysis did not show any statistically significant differences between the obtained results of Young's modulus depending on the respective reagents applied. It was confirmed that different methods of acellularization and the process of sterilization effect the alteration of mechanical properties of allogeneic skins. In the case of the decellularization method using SDS (Sodium Dodecyl Sulfate), liquid nitrogen and 85% glycerol the highest values of strain were observed. In the authors' opinion, it is the above-mentioned methods that should be recommended in the process of preparation of skin substitutes.

Method of creating 3D models of small caliber cerebral arteries basing on anatomical specimens.

The cerebral circulation is a common site of vascular lesions and concurrent hemodynamic accidents, which often lead to serious neurological disabilities. Recent advances in understanding pathogenesis, improving diagnostics and developing new treatment methods for these conditions result from an interdisciplinary approach to the problem - linking clinical sciences, basic medical sciences and hemodynamical analyses. Most common techniques used in such studies include computational fluid dynamics, which allows for development of 3D models of cerebral vasculature, basing on radiological studies. However, these methods remain flawed, mainly because of their spatial resolution, which is not high enough to visualize the smallest arterial branches (perforating branches) in the models. That leaves the perforators (<1.0 mm) out of most of the contemporary studies, whilst their clinical importance is widely recognized in clinical practice. Obstruction of these vessels by atherosclerotic plaques, thrombi or implantation of flow diverting stents may result in neurological complications such as paralysis or coma. Our research team has recently developed a new method of creating 3D models of the cerebral arterial system based on anatomical specimens and micro computed tomography (micro-CT). We have infused fresh brainstem vasculature specimens with contrast medium, subsequently scanned them using an industrial-grade micro-CT system and finally, created spatial models, which included branches of diameter less than 0.1 mm. None of the current methods have been able to produce models of detail as high as this, which allows us to presume, that our procedure may open up new opportunities for hemodynamical studies within cerebral circulation and beyond.

Evaluation of the effect of muscle forces implementation on the behavior of a dummy during a head-on collision.

PURPOSE: The aim of this study was to develop a method to implement muscle forces to a numerical model of a dummy and to evaluate the effect of muscle activation on driver behavior during a frontal collision. The authors focused on the forces acting at the knee, hip, and elbow joints. METHODS: The authors carried out torque measurements in joints using the Biodex System 4. Then, the previously developed numerical models were modified by introducing the joint torque values. Moments of force were introduced as a function of the rotation angle. During research, numerical simulations were carried out in three stages: in the first stage, a full vehicle crash was analyzed to determine the change of velocity of the vehicle interior; in the second stage, subsidence of the system was realized; in the third stage, a frontal crash was simulated. The models considered the operation of the sensors, airbag and seat belt tensioning system. RESULTS: A numerical model with the active response of the dummy to the change in position during impact was developed. The results of the dynamic analysis were used to analyze the impact of muscle activation on dummy behavior. The change in shoulders rotation angle, the lateral and vertical displacement of the dummy's center of gravity, and the forces acting between the dummy and the seat belt were compared. CONCLUSIONS: The effect of muscle action on the behavior of a dummy during a frontal collision was determined.

Deformation Process of 3D Printed Structures Made from Flexible Material with Different Values of Relative Density.

The main aim of this article is the analysis of the deformation process of regular cell structures under quasi-static load conditions. The methodology used in the presented investigations included a manufacturability study, strength tests of the base material as well as experimental and numerical compression tests of developed regular cellular structures. A regular honeycomb and four variants with gradually changing topologies of different relative density values have been successfully designed and produced in the TPU-Polyflex flexible thermoplastic polyurethane material using the Fused Filament Fabrication (FFF) 3D printing technique. Based on the results of performed technological studies, the most productive and accurate 3D printing parameters for the thermoplastic polyurethane filament were defined. It has been found that the 3D printed Polyflex material is characterised by a very high flexibility (elongation up to 380%) and a non-linear stress-strain relationship. A detailed analysis of the compression process of the structure specimens revealed that buckling and bending were the main mechanisms responsible for the deformation of developed structures. The Finite Element (FE) method and Ls Dyna software were used to conduct computer simulations reflecting the mechanical response of the structural specimens subjected to a quasi-static compression load. The hyperelastic properties of the TPU material were described with the Simplified Rubber Material (SRM) constitutive model. The proposed FE models, as well as assumed initial boundary conditions, were successfully validated. The results obtained from computer simulations agreed well with the data from the experimental compression tests. A linear relationship was found between the relative density and the maximum strain energy value.

Experimental Tests, FEM Constitutive Modeling and Validation of PLGA Bioresorbable Polymer for Stent Applications.

The use of bioresorbable polymers such as poly(lactic-co-glycolic acid) (PLGA) in coronary stents can hypothetically reduce the risk of complications (e.g., restenosis, thrombosis) after percutaneous coronary intervention. However, there is a need for a constitutive modeling strategy that combines the simplicity of implementation with strain rate dependency. Here, a constitutive modeling methodology for PLGA comprising numerical simulation using a finite element method is presented. First, the methodology and results of PLGA experimental tests are presented, with a focus on tension tests of tubular-type specimens with different strain rates. Subsequently, the constitutive modeling methodology is proposed and described. Material model constants are determined based on the results of the experimental tests. Finally, the developed methodology is validated by experimental and numerical comparisons of stent free compression tests with various compression speeds. The validation results show acceptable correlation in terms of both quality and quantity. The proposed and validated constitutive modeling approach for the bioresorbable polymer provides a useful tool for the design and evaluation of bioresorbable stents.

Numerical and experimental analysis of balloon angioplasty impact on flow hemodynamics improvement.

PURPOSE: The paper focuses on the numerical and experimental evaluation of the fluid flow inside chosen fragments of blood vessels. In the first stage of the study, the experimental tests were conducted using a research test stand, designed to be used in this evaluation. The study evaluated the blood flow through a silicone vessel with an implanted coronary stent. METHODS: The PIV method was used in order to visualize the flow vectors inside a silicone vessel. Deformed vessel geometry implemented for computational fluid dynamics purposes was obtained owing to a non-linear simulation of the stent expansion (angioplasty process) in a silicone vessel. Additionally, a vessel model with a statistical 55% area stenosis and an irregular real vessel with an atherosclerotic plaque were also subjected to analysis from the hemodynamic flow point of view. A vessel with a statistical stenosis was also used to simulate the angioplasty process, which resulted in obtaining a flow domain for the vessel with an atherosclerotic plaque after the stent implantation. RESULTS: For each case, distributions of parameters such as OSI or TAWSS were also analyzed and discussed. The areas of low TAWSS values appear close to the stent struts. CONCLUSIONS: Stents with increased diameters, compared to the normal vessel diameter, create a higher risk of occurrence of the areas with low WSS values. Excessive stent deformation can cause inflammation by injuring the vessel and can initiate the restenosis and thrombotic phenomena through the increased vessel diameter.

Static and Dynamic Loading Behavior of Ti6Al4V Honeycomb Structures Manufactured by Laser Engineered Net Shaping (LENSTM) Technology.

Laser Engineered Net Shaping (LENSTM) is currently a promising and developing technique. It allows for shortening the time between the design stage and the manufacturing process. LENS is an alternative to classic metal manufacturing methods, such as casting and plastic working. Moreover, it enables the production of finished spatial structures using different types of metallic powders as starting materials. Using this technology, thin-walled honeycomb structures with four different cell sizes were obtained. The technological parameters of the manufacturing process were selected experimentally, and the initial powder was a spherical Ti6Al4V powder with a particle size of 45-105 µm. The dimensions of the specimens were approximately 40 × 40 × 10 mm, and the wall thickness was approximately 0.7 mm. The geometrical quality and the surface roughness of the manufactured structures were investigated. Due to the high cooling rates occurring during the LENS process, the microstructure for this alloy consists only of the martensitic α' phase. In order to increase the mechanical parameters, it was necessary to apply post processing heat treatment leading to the creation of a two-phase α + ß structure. The main aim of this investigation was to study the energy absorption of additively manufactured regular cellular structures with a honeycomb topology under static and dynamic loading conditions.

Identification of Mechanical Properties for Titanium Alloy Ti-6Al-4V Produced Using LENS Technology.

This paper presents a characterization study of specimens manufactured from Ti-6Al-4V powder with the use of laser engineered net shaping technology (LENS). Two different orientations of the specimens were considered to analyze the loading direction influence on the material mechanical properties. Moreover, two sets of specimens, as-built (without heat treatment) and after heat treatment, were used. An optical measurement system was also adopted for determining deformation of the specimen, areas of minimum and the maximum principal strain, and an effective plastic strain value at failure. The loading direction dependence on the material properties was observed with a significant influence of the orientation on the stress and strain level. Microstructure characterization was examined with the use of optical and scanning electron microscopes (SEM); in addition, the electron backscatter diffraction (EBSD) was also used. The fracture mechanism was discussed based on the fractography analysis. The presented comprehensive methodology proved to be effective and it could be implemented for different materials in additive technologies. The material data was used to obtain parameters for the selected constitutive model to simulate the energy absorbing structures manufactured with LENS technology. Therefore, a brief discussion related to numerical modelling of the LENS Ti-6Al-4V alloy was also included in the paper. The numerical modelling confirmed the correctness of the acquired material data resulting in a reasonable reproduction of the material behavior during the cellular structure deformation process.

Sensitivity study on seat belt system key factors in terms of disabled driver behavior during frontal crash.

PURPOSE: Each year, many cars (in Poland approximately three hundred) are adopted for disabled driver, to enable them to drive the car independently. The purpose of the paper is to assess the key factors which significantly influence the disabled driver behavior during a frontal crash and have the biggest impact on the safety factors. METHODS: To achieve the purpose of the paper, the finite element method was used. The authors built the numerical model which includes operation of all safety systems operating in the real car (sensors, seat belts, airbag). Using this method, the authors simulated few different cases of the frontal crash of the car driven by a person with disabilities. RESULTS: The obtained results were: displacements, velocities and accelerations of the head, pelvis and shoulders. Additional results were also loads in the neck. Based on the achieved results, several biomechanical parameters and criterions (HIC, Nij) were computed. CONCLUSIONS: Therefore, during car adaptation for disabled drivers using a four-point seat belts system, this parameter can be optimized to reduce forces acting on the driver chest. Higher values of the force limit reduce Nij and increase HIC and contact forces between the dummy and seatbelts. Therefore, during designing of the pyrotechnic four-point seat belts system, the pretensioner characteristics should be analyzed taking all the driver's biomechanical parameters into account.

The effects of types of guidewires and pressure applied during stent implantation in the main vessel on the incidence of damage to coronary guidewires during angioplasty of coronary bifurcation lesions-Wide Beast study.

OBJECTIVES: We evaluated the impact of stent inflation pressure and type of guidewire on "jailed" coronary guidewire damage occurring during bifurcation angioplasty. BACKGROUND: Despite new techniques and treatment options during percutaneous coronary intervention (PCI) we still observe peri- and postoperative complications for to various known and unknown reasons. METHODS: Patients undergoing PCI within the coronary bifurcation were randomly assigned to one of four groups: Pilot 50 or BMW guidewire and pressure ≤12 or >12 atm. After PCI each "jailed" guidewire was evaluated under an optical microscope. The Wide Beast Scale (WBS) was developed for the internal purposes of the study and was used for qualitative assessment. Also, the inflation pressure, the patients' characteristics and the technical parameters of the procedure were recorded. RESULTS: The clinical characteristics were similar in all the groups. There was no statistical significance of the degree of damage, rated on the WBS, for either guidewire group with respect to inflation pressure (P = 0.49). The prevalence of guidewire damage was higher in the BMW versus the Pilot 50 group (98.4% vs 67.4% respectively, P = 0.00001) as was the severity of the damage (grades 3 and 4) in BMW versus Pilot 50 (55.6% vs 13.0% respectively, P = 0.00001). CONCLUSIONS: The inflation pressure during stent implantation had no impact on "jailed" guidewire damage. The difference in the prevalence of serious damage and total damage number was statistically significant for the BMW guidewire compared to the Pilot50. The BMW guidewire was an independent predictor of the degree of damage to the guidewire.

Analysis of mechanics of side impact test defined in UN/ECE Regulation 129.

OBJECTIVE: This article discusses differences between a side impact procedure described in United Nations/Economic Commission for Europe (UN/ECE) Regulation 129 and scenarios observed in real-world cases. METHODS: Numerical simulations of side impact tests utilizing different boundary conditions are used to compare the severity of the Regulation 129 test and the other tests with different kinematics of child restraint systems (CRSs). In the simulations, the authors use a validated finite element (FE) model of real-world CRSs together with a fully deformable numerical model of the Q3 anthropomorphic test device (ATD) by Humanetics Innovative Solution, Inc. RESULTS: The comparison of 5 selected cases is based on the head injury criterion (HIC) index. Numerical investigations reveal that the presence of oblique velocity components or the way in which the CRS is mounted to the test bench seat fixture is among the significant factors influencing ATD kinematics. The results of analyses show that the side impact test procedure is very sensitive to these parameters. A side impact setup defined in Regulation 129 may minimize the effects of the impact. CONCLUSIONS: It is demonstrated that an artificial anchorage in the Regulation 129 test does not account for a rotation of the CRS, which should appear in the case of a realistic anchorage. Therefore, the adopted procedure generates the smallest HIC value, which is at the level of the far-side impact scenario where there are no obstacles. It is also shown that the presence of nonlateral acceleration components challenges the quality of a CRS and its headrest much more than a pure lateral setup.